A 6-month-old female infant presented with multiple, slightly depressed pea-sized erythematous macules on the abdomen and the chest since birth, which together with obese, short stature, short neck, and round face suggested Albright's hereditary
osteodystrophy(AHO). Some of the lesions were palpable as hard nodules or plaques in deep dermis. After 3 months follow up, the erythematous hue faded out, subcutaneous nodules and plaques enlarged. Skin biopsy specimen demonstrated a bone
formation in
deep dermis. Serum calcium and phosphorus levels were lower and upper normal ranges, respectively and serum parathyroid hormone was increased in 69.1 pg/ml (normal, 9-55pg/ml). As pseudohypoparathyroidism including this case mostly exhibit
characteristic morphologic features of AHO, the subcutaneous ossification may be a presenting feature.
(Kor J Dermatol 1996;34(5) : 842~846)
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